PRECISE PROTEOMICS
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1 / HMGB1 - February 2023
Pirnie R, P Gillespie K, Mesaros C, Blair IA. Reappraisal of oxidized HMGB1 as a mediator and biomarker. Future Sci OA. 2023 Feb 10;8(10):FSO828. doi: 10.2144/fsoa-2022-0052. PMID: 36874369; PMCID: PMC9979160.
Rojsajjakul T, Wu L, Grady CB, Hwang WT, Mesaros C, Lynch DR, Blair IA. Liquid Chromatography-Mass Spectrometry Analysis of Frataxin Proteoforms in Whole Blood as Biomarkers of the Genetic Disease Friedreich's Ataxia. Anal Chem. 2023 Feb 28;95(8):4251-4260. doi: 10.1021/acs.analchem.3c00091. Epub 2023 Feb 17. PMID: 36800320; PMCID: PMC9979142.
Pirnie R, Gillespie KP, Weng L, Mesaros C, Blair IA. Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen. Chem Res Toxicol. 2022 Oct 17;35(10):1893-1902. doi: 10.1021/acs.chemrestox.2c00161. Epub 2022 Aug 3. PMID: 35922039; PMCID: PMC9580022.
Wang Q, Laboureur L, Weng L, Eskenazi NM, Hauser LA, Mesaros C, Lynch DR, Blair IA. Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood. Front Neurosci. 2022 Apr 28;16:874768. doi: 10.3389/fnins.2022.874768. PMID: 35573317; PMCID: PMC9098139.
Weng L, Laboureur L, Wang Q, Guo L, Xu P, Gottlieb L, Lynch DR, Mesaros C, Blair IA. Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich's ataxia. Sci Rep. 2020 Sep 25;10(1):15788. doi: 10.1038/s41598-020-72884-w. PMID: 32978498; PMCID: PMC7519113.
Weng L, Wang Q, Yu S, Yang X, Lynch DR, Mesaros C, Blair IA. Evaluation of antibodies for western blot analysis of frataxin protein isoforms. J Immunol Methods. 2019 Nov;474:112629. doi: 10.1016/j.jim.2019.07.001. Epub 2019 Jul 4. PMID: 31279523; PMCID: PMC6829029.
Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Mesaros C, Lynch DR, Blair IA. Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes. Sci Rep. 2018 Nov 19;8(1):17043. doi: 10.1038/s41598-018-35346-y. PMID: 30451920; PMCID: PMC6242848.
Weng L, Guo L, Vachani A, Mesaros C, Blair IA. Quantification of Serum High Mobility Group Box 1 by Liquid Chromatography/High-Resolution Mass Spectrometry: Implications for Its Role in Immunity, Inflammation, and Cancer. Anal Chem. 2018 Jun 19;90(12):7552-7560. doi: 10.1021/acs.analchem.8b01175. Epub 2018 Jun 5. PMID: 29791130; PMCID: PMC6417096.
Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros C, Lynch DR, Blair IA. Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia. Anal Chem. 2018 Feb 6;90(3):2216-2223. doi: 10.1021/acs.analchem.7b04590. Epub 2018 Jan 11. Erratum in: Anal Chem. 2019 Feb 5;91(3):2560. PMID: 29272104; PMCID: PMC5817373.